Tempus Labs, Inc. is hiring a
Bioinformatics Analyst

Summary

Join a team passionate about precision medicine and advancing the healthcare industry. We are seeking a highly motivated and capable bioinformatics analyst with experience and interest in translational cancer research and next-gen sequencing clinical diagnostics.

Requirements

• BS/BA in bioinformatics, computer science, molecular biology or genetics, or equivalent field of study
• Programming skills: SQL, Bash, Python
• Computational biology skills using Python
• Experience working with next-generation sequencing data
• Familiarity with Mac/Linux working environment

Responsibilities

• Provide bioinformatics support for quality control and variant identification/interpretation, prior to clinical case sign-outs
• Evaluate sample and variant metrics to confirm data quality and integrity
• Provide timely notifications to laboratory and clinical personnel regarding potential sample irregularities
• Interpretation of single-nucleotide, insertion/deletion, and copy number variants, as well as variants predictive of protein fusion events, in both DNA and RNA data
• Responsible for identifying and interpreting complex variant calls in low coverage, variable, and novel genomic regions, in addition to sequencing artifacts
• Use SQL and other scripting languages to retrieve relevant data from various bioinformatics databases
• Use Python to perform analyses on genomic data sets and maintain internal tools
• Communicate findings in a clear and logical manner to help stakeholders make scientific and clinical decisions based on your interpretation of variant data
• Produce high-quality, detailed documentation for analyses/projects
• Track variant data through multiple systems, utilize code searches, and review documentation, to understand how a result was produced

Preferred Qualifications

• Advanced degree in Bioinformatics, computational biology, genomics, or equivalent field of study
• Work experience in cancer genetics or molecular biology
• Familiarity with next-gen sequencing lab practices
• Previous experience working with next-gen sequencing data
• Capacity to excel in an interdisciplinary team environment
• Software development experience using Github
• Experience with communicating insights and presenting concepts to a diverse audience
• Familiarity with cloud computing environments
• Understanding of DNA variant nomenclatures (HGVS, VCF, etc.)