Orca is hiring a
Bioprocess Development Associate

Summary

The Bioprocess Development Associate will develop and optimize protein and protein-conjugate manufacturing processes at Orca Bio, a late-stage biotechnology company focused on redefining the transplant process for blood cancer patients. The role involves designing, optimizing, and implementing process improvements related to protein production and bioconjugation, collaborating with multiple teams, maintaining detailed records, and troubleshooting issues.

Requirements

• Bachelor’s degree in Chemical Engineering, Biotechnology, Biochemistry or related field
• 2-5 years of experience in process sciences or manufacturing
• Competence in aseptic technique, mammalian seed train maintenance, media, buffer preparation, and using lab equipment including laminar flow hoods, incubators, autoclaves
• Hands on experience with analytical techniques for antibody characterization, processing and analyzing samples
• Experience executing cell culture experiments, antibody expression and purification
• Willingness to learn flow cytometry for analysis of cell populations
• Willingness to work in a BSL-2 environment

Responsibilities

• Design, optimize and implement process improvements related to protein production and bioconjugation of protein-protein complexes
• Design and execute studies to develop and optimize cell culture and purification steps; perform analytical testing; preform troubleshooting and investigations; perform stability and formulation studies
• Collaborate with external vendors and internal teams to design and implement novel technologies for optimizing protein-conjugate development
• Support continuous improvements of records and follow operating procedures with strong attention to detail
• Maintain detailed records of experiments, have good data management and documentation skills
• Instrument set-up and preparation, maintenance, troubleshooting, and operation

Preferred Qualifications

• Experience with bioconjugation and DoE methodology
• Familiarity with immunology concepts
• Flow Cytometry experience

Benefits

• The anticipated annual salary range for this job is $65,000 - $85,000, based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law
• You will also be eligible to receive pre-IPO equity, in addition to medical, dental, and vision benefits, flexible PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits
• Other perks include free daily lunches and snacks at our on-site locations