Day One Biopharmaceuticals is hiring a
Director Clinical Pharmacology

Summary

The job description is for a Director, Clinical Pharmacology position at Day One Biopharmaceuticals. The role involves leading the ADC program and serving as a strategic leader in a matrix environment. The position requires a candidate with a PhD, PharmD or equivalent training in Pharmaceutical Sciences and typically 10 years of Clin Pharm experience in the industry.

Requirements

• PhD, PharmD or equivalent training in Pharmaceutical Sciences
• Typically 10 years of Clin Pharm experience in the industry
• Extensive experience with clinical-stage ADC programs
• Strong communication and interpersonal skills

Responsibilities

• Serve as the Clin Pharm lead of the ADC program at the cross-functional team
• Develop in-depth understanding of ADC’s PK/PD characteristics, MoAs, and unmet medical needs of potential indications
• Play a critical role in dose optimization and indication selection in support of early clinical development
• Translate cross-functional team’s questions to specific Clin Pharm questions with well-defined scope of work and clear timelines to execute
• Author and execute Clin Pharm Development Plans in a timely manner
• Author/co-author and review documents such as clinical trial protocols, clinical study reports and regulatory submission packages
• Support Medical Affairs on Day One posters at medical conferences; prepare abstracts and manuscripts for publication
• Address Clin Pharm related questions from medical monitors, investigators, and other cross functional team members
• Lead the Clin Pharm support for discussion and negotiation with Health Authorities
• Identify issues impacting the programs and lead issue resolution
• Influence development programs based on scientific, clinical, and business insights
• Manage junior colleagues/ contractors including development, mentoring, and effective delegation
• If necessary, provide Clin Pharm support to other Day One asset(s)
• If necessary, independently conduct preliminary PK analyses (i.e., NCA) using Phoenix WinNonlin and present the results with summary statistics and figures
• Oversee external vendor(s)

Benefits

The salary range for this position is $220,000 - $240,000