Remote Medical Director, Clinical Development

Summary

Join Kyverna Therapeutics as a Medical Director or Senior Medical Director to contribute to the development of novel engineered T cell-based therapies for autoimmune diseases.

Requirements

• MD (or ex-US equivalent) or MD-PhD degree required. Advanced degree or research experience in immunology preferred
• 5+ years of clinical research experience with 2+ years of industry experience in clinical development involved in the design and execution of clinical trials
• Specialty training in rheumatology and/or industry experience in clinical development of therapeutics in autoimmune diseases
• Proven ability to interpret, discuss and present efficacy and safety data
• Working knowledge of GCP/ICH, clinical trial design, clinical development processes, and regulatory requirements
• Strong ability to communicate and establish effective working relationship with investigators, collaborators, scientific advisors, CROs, and corporate partners

Responsibilities

• Serve as the medical lead for CAR T-cell therapy clinical trials in multiple autoimmune disease indications, in partnership with internal and external cross-functional teams
• Support, as the clinical representative, the transition of preclinical projects to clinical development
• As the clinical trial study physician, be responsible for clinical deliverables and activities, including: Medical monitoring of clinical trials
• Medical review, analysis, and interpretation of safety, efficacy, and PK and biomarker data
• Development of clinical trial documents including protocols, ICFs, clinical development plans, and publications
• Lead the development of clinical sections of regulatory documents including the IB, safety updates, clinical study reports, and responses to Health Authorities
• Actively engage with external investigators and researchers to identify, evaluate, and support investigator sponsored studies and drive research collaborations

Benefits

• Base salary range for candidates residing in California: $240,000 USD to $300,000 USD annually
• Eligible for bonus
• Benefits
• Participation in Company’s stock option plan