Remote Medical Director/Senior Medical Director, Clinical Development

Summary

Join Kyverna Therapeutics as a Medical Director or Senior Medical Director to contribute to the development of novel engineered T cell-based therapies for autoimmune diseases.

Requirements

• MD (or ex-US equivalent) or MD-PhD degree required
• Advanced degree or research experience in immunology preferred
• 5+ years of clinical research experience with 2+ years of industry experience in clinical development involved in the design and execution of clinical trials
• Experience in early clinical development and translational medicine preferred. (2+ years for clinical research experience with 1+ years of industry experience in clinical development for the Medical Director level.)
• Specialty training in rheumatology and/or industry experience in clinical development of therapeutics in autoimmune diseases is highly preferred
• Proven ability to interpret, discuss and present efficacy and safety data
• Working knowledge of GCP/ICH, clinical trial design, clinical development processes, and regulatory requirements
• Strong ability to communicate and establish effective working relationship with investigators, collaborators, scientific advisors, CROs, and corporate partners

Responsibilities

• Serve as the medical lead for CAR T-cell therapy clinical trials in multiple autoimmune disease indications, in partnership with internal and external cross-functional teams
• Support, as the clinical representative, the transition of preclinical projects to clinical development
• As the clinical trial study physician, be responsible for clinical deliverables and activities, including: Medical monitoring of clinical trials. Medical review, analysis, and interpretation of safety, efficacy, and PK and biomarker data. Development of clinical trial documents including protocols, ICFs, clinical development plans, and publications
• Lead the development of clinical sections of regulatory documents including the IB, safety updates, clinical study reports, and responses to Health Authorities
• Actively engage with external investigators and researchers to identify, evaluate, and support investigator sponsored studies and drive research collaborations

Benefits

• $260,000 - $350,000 a year
• Bonus
• Benefits
• Participation in Company’s stock option plan