Senior Principal Scientist, Medicinal Chemistry

Summary

Join Valo Health, a technology company revolutionizing drug discovery, as a Drug Hunter. You will lead drug discovery efforts on programs through the Logica offering, collaborating with a team of experts to identify and prioritize opportunities for novel medicines. Leveraging Valo's unique computational and experimental platform, you will independently drive chemistry efforts, utilizing the OPAL platform for chemical design and optimization. You will also collaborate across disciplines to enhance drug discovery platforms. This role requires extensive medicinal chemistry expertise, advanced academic training, and experience in drug discovery. The salary range is $185,000 - $241,000 USD.

Requirements

• Extensive practical knowledge and expertise in medicinal chemistry and drug discovery with a distinguished record of accomplishment
• Academic training in organic or medicinal chemistry (M.S. or Ph.D. preferred) with 10+ years of drug discovery experience spanning target ID to candidate nomination
• Skill and facility applying current structure- and/or ligand-based computational design approaches; curiosity and excitement to apply new, technology-driven approaches to transform the drug discovery paradigm
• Demonstrated ability to independently lead, work effectively and collaboratively within multifunctional matrix projects teams and to manage work at contract research organizations
• Excellent oral and written communication skills; strong commitment and attention to detail
• Thoughtful decisiveness; comfort and productivity in dynamic and creative environments

Responsibilities

• Lead drug discovery efforts on programs conducted through Logica offering, while providing regular communications to our clients
• Work closely with a team of experienced drug hunters and data scientists to identify and prioritize opportunities for creating novel and impactful medicines
• Independently drive chemistry efforts on Logica programs, using our proprietary OPAL platform to ideate and design chemical spaces to explore, selection and manage the synthesis of molecules to make, and evaluate SAR to optimize drug-like properties
• Collaborate across many disciplines to ideate, plan, build, refine and implement new experimental + computational platforms to enable small molecule drug discovery with unprecedented scope, scale and quality

Benefits

Salary Range: $185,000 — $241,000 USD