Associate Director, Director of Clinical Operations

Summary

Join Caribou Biosciences as an Associate Director/Director of Clinical Operations and lead operational activities for a high-priority hematology program. You will partner with CRO counterparts, manage study-specific meetings, and implement efficiencies to maximize milestone delivery. Responsibilities include reviewing key study metrics, ensuring alignment with company expectations, and managing vendor relationships. This role requires a Bachelor's degree, 8+ years of global clinical trial management experience, and a strong understanding of clinical operations. The ideal candidate will have experience in the CAR-T space and a focus on hematology. This remote-friendly position offers a competitive compensation package, including salary, bonus, equity, generous paid time off, excellent insurance, 401(k), ESPP, and tuition reimbursement.

Requirements

• Bachelor’s Degree is required, in a science or a health-related field
• A minimum of 8 years of global clinical trial management experience within the pharmaceutical or biotechnology industry
• Early phase oncology focus is key, preferably within the hematology space
• In-depth understanding and experience across clinical operations with a track record of success in CRO and vendor delivery oversight
• Being a key contributor to study planning, execution, data cleaning, database locking, study report generation and regulatory inspection
• Ability to lead cross functional study teams in a dynamic, evolving organization
• Excellent communication and interpersonal skills, with the ability to lead and motivate teams and collaborate effectively across functions (internally and externally)

Responsibilities

• Partner with CRO counterparts and assume oversight of the operational activities and deliverables for a key hematology program
• Lead study-specific and cross functional meetings as needed.  These meetings will be purposeful, timely and with clear action or resolution
• Evaluate the current state and leverage full breadth of professional experience to identify (and implement) efficiencies if applicable to maximize delivery of key milestones
• Review key study quality metrics (e.g., eligibility, primary endpoint data, etc.) and follow-up with the Study Team to determine appropriate action, ensuring transparent communication and a solution-oriented approach
• Ensure that decision-making in the day-to-day activities of the CRO and key vendors is in alignment with the company's expectations and identify areas of concern for resolution and/or escalation
• Day-to-day activities may include Updating/reviewing study documents (protocols, informed consent forms, clinical study reports, site facing material, etc.), monitoring study status across internal functions and external vendors, and anticipating and mitigating risks within the timeline, quality, and study budget
• Review, negotiate and approve Clinical Operations' vendors' scopes of work (SOWs) and budgets
• Develop and maintain positive and productive working relationships with investigators and study staff, showcasing Caribou's high quality and ethical standards

Preferred Qualifications

• Prior experience in the CAR-T space, with a specific focus in hematology
• An emphasis on inspection readiness for Clinical Operations
• Ease and confidence in being Investigator and site-facing

Benefits

• Comprehensive compensation package, which includes competitive salary, bonus, and equity for all employees
• Salary Range: $200,000 to $245,000 - This represents the present low and high end of the Company’s pay range for this position. Actual pay will vary based on various factors, including but not limited to location, skill, experience, and performance
• Generous paid vacation time, in addition to company-observed holidays and floating holidays
• Excellent medical, dental, and vision insurance
• 401(k) retirement savings plan, which includes matching employer contributions
• Employee stock purchase plan (ESPP)
• Tuition reimbursement program