Vaxcyte is hiring a
Engineer I in United States

Logo of Vaxcyte
Engineer I
🏢 Vaxcyte
💵 $74k-$90k
📍United States
📅 Posted on Jul 11, 2024


Vaxcyte is seeking an experienced Engineer I to join the Upstream Process Development group within the Protein Development and CMC team. The successful candidate will develop, test, and implement CFPS processes, provide engineering support for new equipment, design and execute upstream CFPS experiments, and more.


  • PhD in Chemical Engineering or a related discipline with 5+ years of relevant Pharma/Biotech industry experience, or MS in Chemical Engineering with 10+ years of relevant Pharma/Biotech industry experience
  • Strong background in cell-free protein synthesis
  • Hands-on experience with CFPS and primary recovery unit operations


  • Develop, test, and implement recipe scripting for CFPS
  • Provide engineering support for selection, commissioning, and qualification of new CFPS-related equipment as well as scale-down models
  • Design and execution of upstream CFPS experiments in various platforms including plate-based assays and SUB pilot bioreactors
  • Author SOPs (standard operating procedure), process flow diagrams, and batch records
  • Analyze and present CFPS data at internal project meetings
  • Participate in upstream database management and documentation in electronic notebooks
  • Develop CFPS scale-up/down models to support technology transfer and manufacturing activities

Preferred Qualifications

Knowledge of ambr-250 bioreactor system a plus


The compensation package will be competitive and includes comprehensive benefits and an equity component

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