Lead Bioinformatician

Summary

Join Natera's Women's Health Bioinformatics team as a Lead Bioinformatics Scientist. You will collaborate with bench scientists, design and analyze experiments, provide technical support for assays, and develop algorithms and tools. The role involves working with large genomics datasets, supporting product development, and collaborating with interdisciplinary teams. A Master's degree in bioinformatics with 6 years of experience or a PhD with 3 years is required, along with extensive experience in data analysis tools like Python or R. Natera offers competitive benefits, including comprehensive medical, dental, vision, life, and disability plans, free testing for employees and their families, fertility care benefits, and more.

Requirements

• Master’s degree in bioinformatics with 6 years post-graduate experience, or PhD with 3 years of post-graduate experience
• At least 4 years practical experience with data analysis tools such as Python or R
• Expert knowledge of bioinformatics tools for NGS including all aspects of sequencing QC and secondary analyses including variant calling
• Strong programming and scripting experience in Python, R and shell
• Fluent in all aspects of exploratory data analysis and visualization for complex data sets and ability to distill observations to actionable recommendations
• Deep understanding of NGS workflows from sample extraction to sequencing
• Ability to communicate effectively with wet lab groups and explain clearly technical bioinformatics concepts
• Ability to work independently while managing multiple objectives and timelines
• Desire to work in a fast-paced environment with potential for high impact in a small team

Responsibilities

• Collaborate with bench scientists to design and analyze experiments to evaluate novel assay technologies, and provide independent interpretation and recommendations for assay optimization
• Provide technical support for assays in production, including troubleshooting, QC monitoring and reporting out to lab operations, development and bioinformatics teams
• Develop algorithms and tools as necessary to support development of new products, including contributions to the bioinformatics pipeline
• Act as an internal technical consultant to other functional groups or their members by providing expert advice on bioinformatics methodology
• Work closely with interdisciplinary teams including assay, engineering, biostats, commercial and lab operations to support the development of new products

Preferred Qualifications

• PhD with 3 years of post-graduate experience
• Familiarity with cloud computing and workflow management tools such as SnakeMake, WDL or NextFlow
• Familiarity with typical approaches, best practices, and regulatory standards in CLIA product development design

Benefits

• Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents
• Free testing in addition to fertility care benefits
• Pregnancy and baby bonding leave
• 401k benefits
• Commuter benefits
• Generous employee referral program