Bioinformatics Scientist, NGS

Summary

Join Twist Bioscience as a Bioinformatics Scientist and contribute to the development of innovative computational solutions for processing NGS data and designing novel sequence variants. Collaborate with a team of research scientists, software engineers, and data scientists to accelerate and scale Twist Biopharma Solutions’s offerings. You will develop bioinformatics solutions, utilize data science techniques, and contribute to AI/ML-based solutions for antibody sequence design. The ideal candidate possesses strong coding skills in Python, experience analyzing biological datasets, and a passion for drug discovery using antibodies. This role requires a Master's or PhD in a related scientific discipline with 4-5 years of experience.

Requirements

• Master or PhD in Bioinformatics, Computational Biology, or related scientific discipline with a minimum of 4-5 years related experience
• Strong foundational coding skills in Python
• Demonstrated experience in analyzing biological datasets (e.g., NGS), visualizing the results (e.g., interactive plots), and utilizing common file formats (e.g., FASTA, FASTQ)
• Basic understanding of cloud computing, workflow management systems, and CI/CD pipelines

Responsibilities

• Develop software solutions for storing, querying, processing, and visualizing biological data and sequences
• Utilize data science techniques and frameworks, including modeling (e.g., entity relationship diagrams), analysis (e.g., pandas, numpy, scikit-learn), and visualization (e.g., matplotlib, plotly)
• Contribute to the development of traditional as well as AI/ML-based solutions to design novel antibody sequences
• Collaborate with internal members throughout all phases of R&D workflows, analyzing Bioinformatics requirements, addressing the requirements quickly, and providing technical support
• Follow and establish software development best practices, including specification (gathering requirements), conceptualization, coding, testing, deployment, maintenance, and code versioning/management

Preferred Qualifications

• Understand and/or have a passion for learning drug-discovery approaches using antibodies (e.g., antibody discovery & engineering)
• High interest in learning and contributing to developing web applications (e.g., Django, React) and utilizing database management systems (e.g., PostgreSQL)

Benefits

• Bonus
• Equity
• A generous benefits package