Senior Product Manager

Summary

Join Natera as a Senior Product Manager to spearhead the development and lifecycle management of innovative early cancer detection (ECD) products. You will be pivotal in shaping and executing product strategy for high-impact diagnostics, improving patient outcomes through earlier interventions. Lead cross-functional teams through all product development phases, from feasibility to launch and beyond. This high-ownership role blends strategic vision and technical execution, demanding diagnostics or life sciences industry experience with a proven ability to launch novel, clinically impactful products. You will define product roadmaps, translate clinical insights into requirements, and lead Voice of Customer initiatives. Success requires collaboration with various teams and regular updates to senior leadership.

Requirements

• Bachelor’s degree in a life science, engineering, or relevant technical discipline required; Master’s or advanced degree preferred
• Minimum 5+ years of experience in product management or development within the diagnostics, oncology, or medical device industries
• Experience with regulated products, including IVDs or LDTs, and familiarity with FDA or CLIA regulatory pathways
• Proven ability to manage complex, cross-functional product development efforts in a matrixed environment

Responsibilities

• Lead the product lifecycle for ECD diagnostics, from concept to commercialization, including product definition, planning, and delivery
• Define and execute a strategic product roadmap aligned with clinical and market needs for early cancer detection
• Translate complex clinical and scientific insights into clear product requirements in partnership with R&D, clinical affairs, software engineering, and regulatory teams
• Lead Voice of Customer (VOC) initiatives, competitive analysis, and market research to ensure product differentiation and customer satisfaction
• Define and monitor key product performance indicators (KPIs) such as sensitivity, specificity, and turnaround time; collaborate with cross-functional teams to drive continuous improvement
• Own product development documentation, including user needs, product requirements, and risk assessments
• Collaborate with Clinical and Regulatory Affairs to support study design, data analysis, and regulatory submissions
• Partner with Marketing and Commercial teams to establish value propositions, go-to-market strategy, pricing models, and launch readiness
• Develop financial models and business cases to support portfolio investment decisions and growth opportunities
• Provide regular updates to senior leadership and stakeholders on product development progress, roadmap evolution, and strategic priorities

Preferred Qualifications

• Deep understanding of early cancer detection technologies and clinical workflows strongly preferred
• Strategic thinker with strong executional focus and a track record of delivering impactful products
• Exceptional ability to communicate scientific and technical information to both technical and non-technical audiences
• Strong project and process management skills; detail-oriented with excellent organizational capabilities
• Financial acumen for developing business cases and modeling product economics
• Skilled in Microsoft Office and product management tools; experience with Agile development methodologies is a plus
• Able to influence and align stakeholders across functions, from R&D to commercial

Benefits

• Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents
• Natera employees and their immediate families receive free testing in addition to fertility care benefits
• Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more
• We also offer a generous employee referral program!