BridgeBio is hiring a
Director in United States

Logo of BridgeBio
🏢 BridgeBio
💵 $220k-$320k
📍United States
📅 Posted on Jul 11, 2024


The job is for a highly motivated and experienced DMPK leader to design and execute DMPK strategies to support clinical development programs at QED Therapeutics, an affiliate of BridgeBio Pharma. The position involves serving as the DMPK/BA lead for both early and late-stage pediatric clinical development programs and requires a Ph.D. in Pharmaceutical Sciences or a related discipline with at least 8 years’ industry experience in DMPK/BA focused on small molecules.


  • Ph.D. in Pharmaceutical Sciences, or related discipline with a focus on drug metabolism and pharmacokinetics
  • At least 8 years’ industry experience in DMPK/BA focused on small molecules


  • Serve as DMPK/BA lead for both early and late-stage pediatric clinical development programs
  • Develop and implement DMPK strategies to support NDA/MAA submissions
  • Design, execute and troubleshoot in vitro and in vivo ADME, DMPK, PK/PD studies with CRO to investigate complex mechanistic ADME for small molecule drugs
  • Analyze, interpret, report DMPK study data, and present DMPK study results internally to project teams and externally to stakeholders/collaborators and in regulatory submissions

Preferred Qualifications

Experience with PBPK and PK/PD modeling and extrapolation to pediatric population including infant and toddler is desirable


  • Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts
  • A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
  • An unyielding commitment to always putting patients first. Learn more about how we do this here
  • A de-centralized model that enables our program teams to focus on advancing science and helping patients. Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science
  • A place where you own the vision – both for your program and your own career path
  • A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
  • Access to learning and development resources to help you get in the best professional shape of your life
  • Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
  • Flexible PTO
  • Rapid career advancement for strong performers
  • Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time
  • Partnerships with leading institutions
  • Commitment to Diversity, Equity & Inclusion
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